Search results for "total IgE"

showing 4 items of 4 documents

Total IgE levels are linked to the response of chronic spontaneous urticaria patients to omalizumab

2018

Urticariabusiness.industryImmunologyUrticària -- TractamentTotal igeOmalizumabOmalizumabImmunoglobulin E030207 dermatology & venereal diseases03 medical and health sciences0302 clinical medicineText mining030228 respiratory systemAnti-Allergic AgentsChronic DiseaseImmunologyHumansImmunology and AllergyMedicineDrug Monitoringbusinessmedicine.drug
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Gender-Dependent Effect of GSTM1 Genotype on Childhood Asthma Associated with Prenatal Tobacco Smoke Exposure

2014

It remains unclear whether the GSTM1 genotype interacts with tobacco smoke exposure (TSE) in asthma development. This study aimed to investigate the interactions among GSTM1 genotype, gender, and prenatal TSE with regard to childhood asthma development. In a longitudinal birth cohort in Taiwan, 756 newborns completed a 6-year follow-up, and 591 children with DNA samples available for GSTM1 genotyping were included in the study,and the interactive influences of gender-GSTM1 genotyping-prenatal TSE on childhood asthma development were analyzed. Among these 591 children, 138 (23.4%) hadphysician-diagnosed asthmaat 6 years of age, and 347 (58.7%) werenull-GSTM1. Prenatal TSE significantly incre…

MalePediatricsmedicine.medical_specialtyArticle Subjectanimal diseasesTaiwanlcsh:MedicineComorbidityLower riskPolymorphism Single NucleotideGeneral Biochemistry Genetics and Molecular BiologyPregnancyRisk FactorsGenotypePrevalencemedicineHumansGenetic Predisposition to DiseaseSex DistributionChildneoplasmsGenotypingGlutathione TransferaseAsthmaChildhood asthmaintegumentary systemGeneral Immunology and Microbiologybusiness.industrylcsh:RTobacco smoke exposureInfant NewbornInfantTotal igeGeneral Medicinemedicine.diseaseAsthmanervous system diseasesCausalityChild PreschoolPrenatal Exposure Delayed EffectsFemaleTobacco Smoke PollutionbusinessBirth cohortResearch ArticleBioMed Research International
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Clinical course of rhinitis and changes in vivo and in vitro of allergic parameters in elderly patients: a long-term follow-up study

2012

Changes in rhinitis symptom severity tend to decrease with aging, but whether the decrease is associated with allergic skin test reactivity, serum total and specific IgE, and nasal eosinophils or determined only by aging is poorly understood. The aim of the study was to analyze sensitivity in vivo and in vitro some 15 years after primary testing, skin prick test (SPT), serum total and specific IgE, ratio sIgE/tIgE, and nasal eosinophils in order to evaluate changes due to age and changes due to the severity of rhinitis symptoms. One hundred and eight rhinitis patients who had been investigated in 1995 were re-interviewed and their current allergy re-assessed after a follow-up of 15 years. A…

AdultMaleAgingmedicine.medical_specialtyAllergySettore MED/09 - Medicina InternaRhinitis Allergic PerennialMucous membrane of noseImmunoglobulin ESeverity of Illness IndexGeneral Biochemistry Genetics and Molecular BiologySerum total IgEIn vivoInternal medicineSeverity of illnessAllergic rhinitimedicineHumansAgedSkinHematologybiologybusiness.industrySerum-specific IgEAge FactorsClinical courseGeneral MedicineImmunoglobulin EMiddle Agedmedicine.diseaseRhinitis AllergicSymptom scoreIn vitroEosinophil in nasal fluidEosinophilsNasal MucosaItalyImmunologybiology.proteinFemalebusinessFollow-Up StudiesClinical and Experimental Medicine
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Evaluation of serum s-IgE/total IgE ratio in predicting clinical response to allergen-specific immunotherapy.

2009

Background: To date, no predictive tests for the clinical response to allergen-specific immunotherapy (ASI) are available. Therefore an in vivo or in vitro test would be of great value. Objective: We sought to evaluate pretreatment parameters used in diagnosing allergic rhinitis and determining serum specific IgE (s-IgE) levels, serum total IgE (t-IgE) levels, and blood eosinophil counts and to identify whether can be used to predict clinical improvement in monosensitized patients with allergic rhinitis with or without asthma treated with immunotherapy. Methods:We analyzed 279 patients who had undergone 4 years of ASI administered either by means of the subcutaneous immunotherapy (76 patien…

AdultMaleAllergySettore MED/09 - Medicina InternaRhinitis Allergic PerennialAdolescentmedicine.medical_treatmentImmunologyspecific IgEImmunoglobulin Eblood eosinophil countsYoung AdultBlood serummedicineImmunology and AllergyHumansreceiver operating characteristic curveAsthmaDesensitization (medicine)Retrospective StudiesSkin Testsserum s-IgE/total IgE ratio; allergen-specific immunotherapyHouse dust miteserum s-IgE/total IgE ratiobiologyserum-specific IgE/serum total IgE ratiobusiness.industryAllergen-specific immunotherapy; blood eosinophil counts; receiver operating characteristic curve; serum-specific IgE/serum total IgE ratio; specific IgE; total IgEArea under the curveImmunotherapyAllergensImmunoglobulin EMiddle Agedmedicine.diseasebiology.organism_classificationPrognosisAllergen-specific immunotherapyBlood Cell Counttotal IgEEosinophilsTreatment OutcomeDesensitization ImmunologicSpirometryImmunologybiology.proteinFemalebusiness
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